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Keep an eye on Closely (1)pentobarbital will increase the stage or outcome of clopidogrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lower the level or impact of clarithromycin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.pentobarbital will lessen the level or result of